Crohn’s disease: research says marijuana causes complete remission of disease in 45% of cases

“The term” medicinal product “means any substance or combination of substances presented as possessing curative or preventive properties with regard to human or animal diseases, as well as any substance or composition that can be used in humans or in animals or that can be administered to them. , in order to establish a medical diagnosis or to restore, correct or modify their physiological functions by exerting a pharmacological, immunological or metabolic action ….

If, with all its characteristics, a product is capable of satisfying both the definition of the medicinal product provided for in the first paragraph and that of other categories of products governed by Community or national law, it is, in the case of doubt, considered a drug. “

So if new studies are done on this disease and cannabis hope that the possibility of such treatment is taken into account.

According to a new study , cannabis has the capacity to relieve Crohn’s disease and for 45% of patients, there has been a remission.

This study was performed on 21 people with this disease. Half received cigarettes without cannabinoids and the other half received smoking joints. The joints contained 23% THC and 0.5% CBD. 45% of people who smoked joints daily for eight weeks experienced complete remission of Crohn’s disease.

Others reported that the symptoms were about half as important. They could eat and sleep with less pain.

“Subjects receiving cannabis had an improvement in appetite and sleep, with no significant side effects,” the study reports.

This is the first time a placebo trial has been conducted on cannabis and Crohn’s disease. With a little luck, others will follow.

A disease that cannabis can heal.

4 main benefits of cannabis for the treatment of this disease:

Anti-inflammatory

Inflammatory processes are the main mechanism of action of Crohn’s disease.

In various studies, the use of exogenous cannabinoids, including? -THC and CBD, has been shown to activate cannabinoid receptors of the GI tract and participate in the reduction of chronic inflammation.

Antidiarrhéique:

Diarrhea is the most common primary symptom of Crohn’s disease. Depending on the infected part of the GI tract, the stool may be mixed with mucus, pus, or blood, and may be more or less liquid. The feeling of urgency is frequent and is accompanied by the sensation of incomplete evacuation (called tenesmus).

It is likely that activation of CB1 receptors in the GI tract also plays an important role in improving the symptoms of diarrhea by regulating intestinal motility and fluid secretion.

Analgesic:

Nearly 70% of people with Crohn’s disease suffer from chronic pain.

By acting directly on inflammation, reducing the severity of abdominal distension and relieving diarrhea symptoms by reducing intestinal spasms and inhibiting fluid production, cannabis can help relieve symptoms. pain in patients.

To date, no official study has been conducted on the effects of cannabis on pain associated with Crohn’s disease.

However, several questionnaires and surveys of patients have provided evidence of significant improvements in the management of their pain. In a pilot study, the result was: Cannabis use improved all of the signs and symptoms assessed, including pain – rated at 6.5 out of 10 on a subjective severity scale prior to pregnancy. cannabis use, and only 2 out of 10 after taking cannabis.

Stimulant of appetite (orexigenic)

In one study, patients also reported a marked improvement in their appetite with cannabis, from about 1 in 10 to almost 7 in 10 using the same subjective scale. Loss of appetite is also a common symptom of Crohn’s disease, which is often a consequence of chronic nausea and abdominal pain. (source)

ABOUT CANNABIS The National League Against Cancer says:

Is cannabis a medicine?

Delta-9-tetrahydrocannabinol (THC), the main euphoric substance of cannabis, is sometimes used in the treatment of cancer to improve the quality of life of the patient (pain, lack of appetite, nausea …). Research has shown that THC causes death of human glioma cells (an aggressive brain tumor) by apoptosis (programmed death).

Apoptosis is a process in which the cell destroys itself. Healthy cells are not affected. Cannabidiol (CBD), the second cannabis cannabinoid, apparently reinforces this effect.

THC also appears to have an anti-invasive action. This means that it opposes the proliferation of cancer cells to neighboring tissues. This action can be useful in the case of very invasive cancers.

The antitumor effect of THC and other synthetic and natural cannabinoids is not just about gliomas. He also practices on many other types of cancer. Experiments on animals and on human cell cultures have shown this.

Carcinogenic substances

Cannabis smoke contains to a large extent the same carcinogenic substances as tobacco (aromatic hydrocarbons, nitrosamines, aldehydes, etc.), sometimes in higher concentration.

When smoking cannabis, more carbon monoxide is absorbed than smoking tobacco.

Synthetic methandamide cannabinoid has been shown to intensify the development of lung cancer cells.

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