The puzzle of Alzheimer’s disease is not yet complete but the last pieces are being put in place. And rather well. A few days ago, a team of researchers from the University of Rochester (USA) explained in the journal Science how the brain cleans its toxins during sleep. Thanks to a flushing, or more accurately to increased flow of cerebrospinal fluid, the brain discharges its waste, including beta-amyloid proteins, known to play a role in Alzheimer’s disease.
1 in 6 women, and 1 in 11 men may suffer from this brain disease one day. Lack of restorative sleep causes active degeneration of neurons that fail to restructure or regenerate even after resting.
Sleep is an essential process for the proper functioning of our brain, since when the body relaxes and consolidates sleep and rest, the brain begins its work of stock learning new knowledge acquired during the day. This also allows resting the body and recharging energy to start a new day with optimal development of each of the required activities, whether physical or mental.
If you do not sleep well enough to enjoy a healthy life and well-being, you can probably have various conditions, the main one being Alzheimer’s. Remember that the recommended sleep hours for good rest and productivity are 8 per day.
According to some neurologists, when one does not sleep enough time, the production of proteins that affect the connection between neurons increases, preventing the retention of mental activities that allow the memory of the facts. Alzheimer’s is a disease that especially affects the elderly, because with the passing of time, adults decrease their sleep time, accelerating the production of senile plaques, which require more good cells, thus preventing the correct sending of information between neurons.
The lack of balanced sleep generates an active degeneration of the neurons, but recovering by resting one or two days a week while sleeping more than usual does not work. Indeed, the activation of the production of the brain damage occurs each time that one does not sleep enough, does not restructure and does not regenerate either with the posterior sleep. We must sleep every day an established sleep time.
On the other hand, the lack of sleep is not the only cause: intermittent sleep also causes serious brain problems, because the instability of sleep causes about 25% of neurons to lose. This loss of neurons is not only reflected in Alzheimer’s disease (which will appear in old age), but also in everyday life, during which learning processes will be difficult.
During sleep, the brain performs its function of eliminating toxins, thereby eliminating proteins that accelerate the growth of senile plaques that increase memory loss.
The risk of developing Alzheimer’s disease in older women is greater than the risk of breast cancer. The development of this degenerative disease, in men and women, presents the following figures: one in six women is likely to contract this degenerative disease while one in 11 men is at risk of suffering from it. Alzheimer’s is a high-risk disease, as no effective treatment has been found so far and there is no way to cure or reduce the damage.
Fortunately, there are many ways to improve one’s health through consolidation and balance during sleep, a time that must be quiet and sustainable. It is therefore better to enjoy a deep sleep and eliminate intermittences. One of the things that helps you get enough sleep and rest is to enjoy the light during the day and put yourself in complete darkness when you sleep. It is necessary to see light and darkness to be able to adapt one’s body through a biological clock that is responsible for marking the rhythm of the day and requiring activity and rest when they are needed. A tiny bit of light, even a tiny one, can prevent perfect rest and sleep.
Lack of sleep
A big problem for a proper sleep consolidation is the night and day work schedules, because the biological clock and therefore sleep suffer constant alterations that compromise health and well-being.
Avoid watching television or using the computer during the night, as these two technological devices expose you to a light similar to that of the day, and therefore impairs the development of your sleep, its quality and quantity. You can take a hot shower 30 minutes before going to bed, this will help you relax and get ready for a good sleep. A final recommendation: it is essential to move away from the bed or the place where you sleep any type of electronic device because of the effects of light, noise or others which they have on the health.
As you know, your brain health and good performance crucially depends on the quality and amount of sleep you have on a daily basis. Give your schedules and your room in order to have a quality sleep that guarantees your mental and physical well-being.
Study on 28,000 people
The impact of sleep time on memory and cognitive performance was the subject of a large joint study of Hong Kong University and Birmingham between 2003 and 2008 involving more than 28,000 people aged 50 to 85. years. The Chinese who had the best test results were those who slept 7 or 8 hours a day, which was the case for one in two people. Performance decreased significantly for those who slept more than 10 hours or less than 5 hours per day. Waking up tired was also associated with poorer outcomes, perhaps reflecting sleep that was not sufficiently recuperating.
Can we then speculate on a beneficial effect of sleep while waiting to have all the pieces of the puzzle? Especially since some people may have amyloid deposits without signs of disease. “It would be premature to say that improving people’s sleep reduces the deposition of beta-amyloid proteins in the brain or delays the onset of Alzheimer’s disease,” says Dr. Spira. “However, he adds, the work of some research teams suggests at least this possibility. It will take more to confirm it. “
What are the other causes of Alzheimer’s disease?
What are the different hypotheses?
Several tracks are under investigation. None, however, alone succeeds in explaining the onset of Alzheimer’s disease.
-Family antecedents: the risk of being reached increases if a family member is affected, it is to explore more precisely why this increase.
– The body: several hypotheses make a bad functioning of the body the cause of Alzheimer’s disease. For example, for some, the deficit of a nervous messenger, acetylcholine, is due to a decrease in the amount of an enzyme. Others argue that Alzheimer’s disease could be caused by a virus, or the presence of immune cells that turn against the body itself (autoantibody), or by an accelerated mechanism of death of neurons.
– The environment: scientists are looking for toxins that would be involved. For a long time, it was believed a deleterious role of aluminum but it has never been confirmed.